Company Overview
Immunocore is a leading biotech company advancing first-in-class T cell receptor (TCR) therapies to tackle unmet needs in cancer, infectious diseases, and autoimmune conditions.
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Senior Director, Physician – Clinical Development, Late-Stage Oncology
Your Impact: Drive Immunocore’s late-stage oncology programs and shape our clinical science capabilities. You’ll lead strategic planning and oversee the design and medical aspects of clinical studies, from protocol development to regulatory submissions. Your expertise will be crucial in innovative trial design, including biomarker strategies, and you’ll be a key in-house oncology expert collaborating across R&D. This role involves significant leadership and interaction with internal teams, academic leaders, external experts, and global regulatory authorities.
Key Responsibilities:
- Lead the development and execution of clinical development strategies and plans for oncology programs.
- Design innovative, high-quality clinical trial protocols and related documents.
- Build and maintain strong relationships with key opinion leaders and external partners.
- Provide medical oversight for clinical studies, including safety monitoring and data interpretation.
- Offer strategic clinical leadership to development teams, integrating scientific, regulatory, and stakeholder input.
- Collaborate with CROs to ensure efficient and high-quality trial execution.
- Contribute to regulatory strategy and submissions, and participate in health agency meetings.
- Support publication planning and present clinical data at key forums.
- Participate in Business Development activities as needed.
Experience & Knowledge:
- Proven ability to build collaborative relationships and effectively guide teams.
- MD or MD/PhD with a strong clinical perspective and a successful track record in oncology drug development.
- Strategic and critical thinker with experience designing innovative trials leading to successful regulatory filings.
- Established global and local medical community network with strong KOL relationships.
- Excellent communication and professional presence, with the ability to engage diverse stakeholders.
- Collaborative and motivational leader for cross-functional teams.
- Strong problem-solving and analytical skills.
- Thorough knowledge of GCP, ICH, GDP, and relevant regulations (MHRA/EMA/CHMP a plus).
- Comprehensive understanding of the drug development process and clinical document development.
Education & Qualifications:
- MD or MD/PhD with research training/experience.
- Strong understanding of basic and clinical science, pharmacokinetics, biomarkers, statistical principles, and regulatory requirements.
- Broad oncology knowledge; immuno-oncology and hematology fellowship highly desirable.
- Minimum 5 years of relevant clinical drug development experience in the pharmaceutical industry (including late-phase trials).
- Minimum 2 years of experience as a medical monitor in biotech/pharma or a CRO.